Select Currency
Translate this page


Format: MS WORD  |  Chapter: 1-5  |  Pages: 75  |  884 Users found this project useful  |  Price NGN3,000





Diabetes mellitus is a deliberating disorder in which strick glycemic control and prevention of associated complications are very important. In view of the increasing interest in the use of plant source for the treatment of diabetes mellitus, the effect of Garcinia kola extract in blood glucose and serum cholesterol level on alloxan induced diabetic albino rat were investigated.In this research work sixteen albino rat of wistar strain were divided into four groups of four rat in each group. Group one serves as negative control which were non diabetic, and they receives normal poultry feed and 3% tween 80, group two and three which serves as the test were induced alloxan monohydrate to make them diabetic and they received 200mg/kg body weight and 500mg/kg bosdy weight of the ethanolic extract of Garcinia kola respectively and group four serves as standard group, they were induced alloxan monohydrate to be diabetic and they received 100mg/kg of standard drug (Glucoghage 500mg/kg). Alloxan monohydrate caused significant increase in the level of blood glucose, the level of blood glucose were monitored in test and standard groups after oral administration of the garcinia  kola  extract. The  Blood glucose  significantly lowered in the test groups than that of the standard drug, and there is also a decrease in serum cholesterol of the test groups than that of the standard group.  This shows that Garcinia kola extract offered significant anti-diabetic  and anti cholesterol effect in the rats.



1.1Background of the Study

    Diabetes mellitus is the most important disease involving the endocrine pancreas. Its major Manifestations are disordered metabolism and inappropriate hyperglycemia or high level of blood glucose. Despite all the conventional drugs presently available, the progressive deterioration of diabetes control is such that treatment is still insufficient. Insufficiency of current therapies for the treatment of diabetes, combined with both a lack of trust in conventional medical treatment and an inability of the economy to absorb the cost of pharmaceuticals have created a public interest in dietary supplements.  

Diabetes mellitus is a metabolic disease that involve problem with the hormone insulin (Enrich, 2000). It  is characterized by hyperglycemia, increase protein breakdown, pyuria, weight loss, coma etc. Several fractions such as high calorie diet intake, age, lack of exercise, alcohol consumption and genetic predisposition have been linked with diabetic disease (Enrich, 2000). Diabetes mellitus is among the most common disorder in developed and developing countries. The disease is increasing rapidly in many part of the world. In 2000, according  to   WHO (World Health Organization),at least 171 million people worldwide suffer from from diabetes which correspond to 2.8% of world population. This figure is expected to double in the year 2030. Hyperglycemia in diabetic patients is associated with alternation in glucose and lipid metabolism and modification in liver enzyme levels (Jenson and Stenders,1998). Diabetes mellitus has been recognized as a risk factor for cardiovascular Diseases(CVD), such as  stroke, heart attarck, atherosclerosis (Adaramoye and Forambi, 2005). About 75% of death among men and 57% of death among women with diabetes mellitus are attributable to cardiovascular diseases.

Garcinia kola otherwise called bitter kola belongs to the family Guttiferae .  It is  found  mainly in the tropical rain forest region of the central and West Africa . It is predominant in the  rainforest belt of southern Nigeria. The seed are edible and are consumed as adjuvant to the true  kola  (Kola nitida) and for medicinal purposes. Garcinia kola  is regaSrded as a wonderful  kola  because  every part of it has a medicinal importance. Garcinia kola  is used in folklore remedies for the treatment of ailments such as liver disorders, diarrhea, laryngitis, bronchitis and gonorrhea . It is also used in the treatment of jaundice, high fever and purgative. Garcinia kola is masticatory and used to prevent  and relieve colic, chest colds, and cough and can as well be use to treat headache .  Garcinia kola has also anti-fungal and ant-microbial effect (Adaramoye, et al., 2002).

1.2   Aim /Objective

This research aimed at knowing the effect of garcinia kola S extract on blood glucose and serum cholesterol level  in alloxan induced albino rats.

1.3   Significance of Study    

Due to increase rate of diabetes mellitus, this present research work was carried out to circulate the knowledge of medical impact of Garciara kola seedon blood glucose and serum cholesterol levels and to discover an alternative way of treatind diabetes without conventional drugs.

Most times ethnomedical practitioners administer this plant extract being ignorant of the effect it may have in human body.

1.4   Statement of Problem

Lack of finance and unavailability of synthetic anti-diabetic drugs has lead to mortality and morbidity in diabetic patients.

Continuous use of synthetic anti-diabetic drugs causes side effect and toxicity. The need to develop an alternative method of treating diabetes mellitus  without side effect and toxicity is required. These statement thereby prompt the need to research an alternative means of treating diabetes mellitus with low cost, no side effect and also no toxicity.

1.5   Limitations of Study

This research work is limited on the anti-diabetic effect of Garcinia kola seed extract on blood glucose and serum cholesterol  due to lack of money to further the research, time factor and insufficient research equipments.



Not What You Are Looking For?

For Quick Help Chat with Us Now!

+234 814 010 7220

+233 541 351 187

Here's what our amazing customers are saying

Emmanuel Essential
Kogi state University
I actually took the risk,you know first time stuff But i was suprised i received as requested. I love you guys 🌟 🌟 🌟 🌟
Very Good
Azeez Abiodun
Moshood Abiola polytechnic
I actually googled and saw about iproject master, copied the number and contacted them through WhatsApp to ask for the availability of the material and to my luck they have it. So there was a delay with the project due to the covid19 pandemic. I was really scared before making the payment cause I’ve been scammed twice, they attended so well to me and that made me trust the process and made the payment and provided them with proof, I got my material in less than 10minutes
Very Good
Gbadamosi Solomon Oluwabunmi
Swift delivery within 9 minutes of payment. Thank you project master
Ajayi Crowther University, Oyo
I was scared at first when I saw your website but I decided to risk my last 3k and surprisingly I got my complete project in my email box instantly. This is so nice!!!
Ahmadu Bello University
I wish I knew you guys when I wrote my first degree project, it took so much time and effort then. Now, with just a click of a button, I got my complete project in less than 15 minutes. You guys are too amazing!
Temitayo Ayodele
Obafemi Awolowo University
My friend told me about iprojectmaster website, I doubted her until I saw her download her full project instantly, I tried mine too and got it instantly, right now, am telling everyone in my school about, no one has to suffer any more writing their project. Thank you for making life easy for me and my fellow students... Keep up the good work
Very Good
Stancy M
Abia State University, Uturu
I did not see my project topic on your website so I decided to call your customer care number, the attention I got was epic! I got help from the beginning to the end of my project in just 3 days, they even taught me how to defend my project and I got a 'B' at the end. Thank you so much iprojectmaster, infact, I owe my graduating well today to you guys...
Ibrahim Muhammad Muhammad
Usmanu danfodiyo university, sokoto
It's a site that give researcher student's to gain access work,easier,affordable and understandable. I appreciate the iproject master teams for making my project work fast and available .I will surely,recommend this site to my friends.thanks a lot..!
Dau Mohammed Kabiru
Kaduna State College of Education Gidan Waya
This is my first time..Your service is superb. But because I was pressed for time, I became jittery when I did not receive feedbackd. I will do more business with you and I will recommend you to my friends. Thank you.
Very Good
Joseph M. Yohanna
Thanks a lot, am really grateful and will surely tell my friends about your website.


  • Select 3 Project Topics of your choice from your Department.
  • Submit the 3 topics to your Supervisor for Approval.
  • Call Our Instant Help Desk on +234 814 010 7220 and Get Your Complete Project Material Instantly.
  • All project materials on this website are well researched by professionals with high level of professionalism.


How do i choose a Project Topic?

Look for your department and select any topic of your choice

I have a fresh topic that is not on your website. How do I go about it?

How fast can i get a complete project from your website?

Within 15 minutes if the exact project topic is on our website

Is it a complete research project or just materials?

It is a Complete Research Project i.e Chapters 1-5, Abstract, Table of Contents, Full References, Questionnaires / Secondary Data

One of your topics suites my project, but the case study is different. What do i do?

Call Our Instant Help Desk Now: +234 814 010 7220 and you will be responded to immediately

How do i get my complete project?

Your Complete Project Material will be sent to your Email Address in Ms Word document format

Can I get my Complete Project through WhatsApp?

Yes! We can send your Complete Research Project to your WhatsApp Number

What if my Project Supervisor made some changes to a topic i picked from your website?

Call Our Instant Help Desk Now: +234 814 010 7220 and you will be responded to immediately

Do you assist students with Assignment and Project Proposal?

Yes! Call Our Instant Help Desk Now: +234 814 010 7220 and you will be responded to immediately

What if i do not have any project topic idea at all?

Smiles! We've Got You Covered. Chat with us on WhatsApp Now to Get Instant Help: +234 814 010 7220

How can i trust this site?

We are well aware of fraudulent activities that have been happening on the internet. It is regrettable, but hopefully declining. However, we wish to reinstate to our esteemed clients that we are genuine and duly registered with the Corporate Affairs Commission as "PRIMEDGE TECHNOLOGY". This site runs on Secure Sockets Layer (SSL), therefore all transactions on this site are HIGHLY secure and safe!