Select Currency
Translate this page

ASSESSMENT OF SOME HAEMOTOLOGICAL PARAMETER ON MALARIA PATIENT

Format: MS WORD  |  Chapter: 1-5  |  Pages: 63  |  2279 Users found this project useful  |  Price NGN5,000

  DOWNLOAD THE FULL PROJECT

ABSTRACT

Hematological parameters are measurable indices of the blood that serve as a marker for disease diagnosis. The aim of this study was to evaluate hematological parameters of patients with malaria in Nigeria. This was a prospective study in which the full blood count of patients, with malaria attending the General Hospital Owerri, Nigeria from March to May 2007, were analyzed. Data was analyzed using SPSS version 15.0 software. P value of less than or equal to 0.05 is considered as statistically significant. A total of 100 patients were recruited for the study. Fifty patients had P.falciparum malaria while the remaining was negative and were used as controls. There were more males with malaria (n=30) than females (n=20) and thirty two (64%) were below 5years while 18(36%) were above 5 years. Lymphocyte and monocyte counts were elevated among patients with malaria relative to the control while haemoglobin and platelet levels were significantly decreased (P ≤0.05). The platelet level decreases as the degree of malaria parasitaemia increases. Haemalogical parameters in patients with malaria infection are deranged. Thrombocytopenia could be used to determine presence and severity of malaria.

 

CHAPTER ONE

INTRODUCTION

Malaria is one of the most prevalent human infections worldwide resulting in 225 million cases each year (WHO, 2010). It is caused by protozoa parasite of the genus plasmodium which infects and destroys red blood cells. Four species of plasmodia (P. falciparum, P. malariae, P. ovale and P. vivax) cause malaria in humans of which P. falciparum is the most common cause of morbidity and mortality (Taylor-Robinson, 1998; Das and Pan, 2006).Malaria kills an average of 1 million Patients in Africa annually, Snow et al., (2005). In Nigeria about 96 millionpeople are exposed to malaria, and out of these 64 million people get infected and almost 300,000 deaths are being reported annually in the general population, of which over 100,000 deaths are of Patients (Alaribe et al., 2006). Haematological parameters are measurable indices of blood that serve as a marker for disease diagnosis (Petel et al., 2004). Haematological abnormalities such as anaemia and thrombocytopaenia have been observed in patients with malaria (Ladhani et al. 2002; et al. 2007).

The key feature of the biology of the Plasmodium falciparum, the predominant malaria species, is the ability of the infected red blood cells to adhere to the lining of the small blood vessels (Richard et al., 1998). Such sequestered parasites provide considerable obstruction to tissue perfusion. In addition, it is becoming clear that in severe malaria there may be marked reductions in the deformability of uninfected RBCs (Dondorp et al., 2000). RBCs destruction is an inevitable part of malaria, and anaemia further compromises oxygen delivery. Severe anaemia may arise from multiple poorly understood processes including acute haemolysis of uninfected RBCs and dyserythropoeisis, as well as through the interaction of malaria infection with other parasites infection and with nutritional deficiencies (Dondorp et al., 2000). The aim of this study was to determine changes in the haematological parameters of Patients with malaria infection in Nigerian population of Africa. Alterations in the haematological indices may strengthen the suspicion of malaria, prompting more meticulous search for malaria parasite, and timely institution of specific therapy.

Malaria which is the most prevalent infectious disease in the tropical and subtropical regions of the world is of great public health importance (Mishra et al., 2003; Umar et al., 2007; Mia et al., 2011).The World Health Organization reports that malaria, the deadly parasitic disease is responsible for nearly ninety percent of death in Africa (Ogbodo et al., 2010). One-fifth of infants’ death in Africa is caused by the scourge of malaria (Snow et al., 2005; WHO, 2010). In Nigeria, approximately 0.25 million deaths of Patients under the age of five is caused by malaria yearly (UNICEF, 2009). Typhoid fever which is also endemic in Africa is more severe in infants and the elderly (Preston and Boreszyk, 1994; Gatsing et al., 2006). Both malaria and typhoid exhibit close symptomatology and epidemiology (Nsutebu and Ndumbe, 2001; Brian and Wahinuddin, 2006). The first case of malaria-typhoid co-infection occurred among American soldiers in 1862 (Bynum, 2002). The high incidence and prevalence of malaria-typhoid co-infection became popular almost ten years ago whereas the fact that malaria has been prevalently high is already recognized and accepted (Uneke, 2008). The onset and progression of the malaria infection is characterized by vast alterations in hematological and biochemical parameters (Bidaki and Dalimi, 2003). The World health Organization’s (WHO) criteria acknowledges that some biochemical and hematological features should raise the severity of malaria (World Health Organization, 2000).

In different parts of the world including Nigeria, scientific materials on hematological and biochemical alterations in acute falciparum malaria are available (Mishra et al., 2003; Egwunyenga et al., 2004; Bidaki and Dalimi, 2003; Udosen, 2003), but none have really been reported from Sango-Ota, Ogun State, Nigeria and also scientific information on the impact of malaria-typhoid co-infection on hematological and biochemical parameters are scanty. This study examined the effect of malaria and malaria-typhoid co-infection on some hematological and biochemical indices. The study population includes only the febrile patients that have been clinically said to have malaria and malaria-typhoid co-infection from the results of their malaria and widal tests, respectively.

  DOWNLOAD THE FULL PROJECT

ASSESSMENT OF SOME HAEMOTOLOGICAL PARAMETER ON MALARIA PATIENT

Not The Topic You Are Looking For?



For Quick Help Chat with Us Now!

+234 813 292 6373

+233 55 397 8005


HOW TO GET THE COMPLETE PROJECT ON ASSESSMENT OF SOME HAEMOTOLOGICAL PARAMETER ON MALARIA PATIENT INSTANTLY

  • Click on the Download Button above.
  • Select any option to get the complete project immediately.
  • Chat with Our Instant Help Desk on +234 813 292 6373 for further assistance.
  • All projects on our website are well researched by professionals with high level of professionalism.

Here's what our amazing customers are saying

Abubakar Iliyasu Hashim
Federal college of education pankshin affiliated to university of jos
I am highly impressed with your unquantifiable efforts for the leaners, more grace to your elbow.I will inform my colleagues about your website.
Very Good
Uduak From Uniuyo
IProjectMaster is the best project site for students. Their works are unique and free of plagiarism!
Excellent
Musa From Ahmadu Bello University
Thank you iprojectmaster for saving my life, please keep it up and may God continue to bless you people.
Excellent
Abdulrahman Jibrin
Nti Abaji
Nice one work prompt delivery tanx
Very Good
JONNAH EHIS
Ajayi Crowther University, Oyo
I was scared at first when I saw your website but I decided to risk my last 3k and surprisingly I got my complete project in my email box instantly. This is so nice!!!
Excellent
Abdulrazak Bello Marsha
Usman Dan fodio University
It was quite a better guide for project and paper presentation purpoting. Many thanks.
Average
Samuel From Ajayi Crowther University
You guys just made life easier for students. Thanks alot iprojectmaster.com
Excellent
Merry From BSU
I am now a graduate because of iprojectmaster.com, God Bless you guys for me.
Excellent
Azeez Abiodun
Moshood Abiola polytechnic
I actually googled and saw about iproject master, copied the number and contacted them through WhatsApp to ask for the availability of the material and to my luck they have it. So there was a delay with the project due to the covid19 pandemic. I was really scared before making the payment cause I’ve been scammed twice, they attended so well to me and that made me trust the process and made the payment and provided them with proof, I got my material in less than 10minutes
Very Good
Abraham Ogbanje
NATIONAL OPEN UNIVERSITY OF NIGERIA
At first I was afraid.. But I discovered they are legit. I will bring more patronize
Very Good

FREQUENTLY ASKED QUESTIONS

How do I get this complete project on ASSESSMENT OF SOME HAEMOTOLOGICAL PARAMETER ON MALARIA PATIENT?

Simply click on the Download button above and follow the procedure stated.

I have a fresh topic that is not on your website. How do I go about it?

How fast can I get this complete project on ASSESSMENT OF SOME HAEMOTOLOGICAL PARAMETER ON MALARIA PATIENT?

Within 15 minutes if you want this exact project topic without adjustment

Is it a complete research project or just materials?

It is a Complete Research Project i.e Chapters 1-5, Abstract, Table of Contents, Full References, Questionnaires / Secondary Data

What if I want to change the case study for ASSESSMENT OF SOME HAEMOTOLOGICAL PARAMETER ON MALARIA PATIENT, What do i do?

Chat with Our Instant Help Desk Now: +234 813 292 6373 and you will be responded to immediately

How will I get my complete project?

Your Complete Project Material will be sent to your Email Address in Ms Word document format

Can I get my Complete Project through WhatsApp?

Yes! We can send your Complete Research Project to your WhatsApp Number

What if my Project Supervisor made some changes to a topic i picked from your website?

Call Our Instant Help Desk Now: +234 813 292 6373 and you will be responded to immediately

Do you assist students with Assignment and Project Proposal?

Yes! Call Our Instant Help Desk Now: +234 813 292 6373 and you will be responded to immediately

What if i do not have any project topic idea at all?

Smiles! We've Got You Covered. Chat with us on WhatsApp Now to Get Instant Help: +234 813 292 6373

How can i trust this site?

We are well aware of fraudulent activities that have been happening on the internet. It is regrettable, but hopefully declining. However, we wish to reinstate to our esteemed clients that we are genuine and duly registered with the Corporate Affairs Commission as "PRIMEDGE TECHNOLOGY". This site runs on Secure Sockets Layer (SSL), therefore all transactions on this site are HIGHLY secure and safe!